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Distribution from 1990
In the 1990s, transgender care was a marginal specialization in a few academic centers. The patient group was small, almost exclusively adult men, with methodologically worthless follow-up. On this weak foundation, a global treatment industry was built in the years that followed.
A handful of centers, no evidence
The main centers in 1990 were Charing Cross (London), Tavistock GIDS (London, founded 1989), the VUmc Amsterdam (see Dutch rollout ), Karolinska (Stockholm), and Stanford. Annual patient numbers ranged from the tens to the low hundreds. Surgeries were performed by a handful of surgeons; complication rates were high and rarely documented. The Tavistock model for minors would later end as a global scandal in 2024 with the closure of GIDS .
Johns Hopkins closed its gender clinic in 1979 following an internal evaluation by Jon Meyer, which concluded that surgical outcomes offered no psychological benefit over non-operative care. That closure remained in place for decades—a rare example of clinical learning. WPATH (then HBIGDA) ignored Meyer and continued the medical-affirmative line without conducting similar internal evaluations. In doing so, the WPATH lobby systematically suppressed any signal that the paradigm was failing.
Adult men, classical transsexualism
The patient population was predominantly male and adult — consistent with the Blanchard typology of 1989 (homosexual and autogynephilic types). Women seeking transition were rare; minors were not medically treated. AGP is a paraphilia, not an identity — a factual distinction that was erased from clinical terminology in the 2000s under activist pressure.
The radical shift from predominantly early-onset males to the current predominantly post-pubescent girls (see spread 2010 ) has never been accounted for by any biological explanation. It is a socially contagious pattern — ROGD in Littman's characterization — that can only be explained by peer-cluster dynamics and social media, not by an increase in "real" gender variation.
Methodologically worthless outcome measures
Early follow-up studies (Pfäfflin 1992, Bodlund 1996) were retrospective, small-scale, lacked a control group, and relied on self-reported patient satisfaction. The Cass Review (2024), SBU (2022), and NICE (2020) unanimously conclude that virtually none of these studies meet modern evidence standards . The entire WPATH SOC tradition relies on nothing more than clinical impressions.
Dhejne et al. (2011) found suicide rates in transitioned individuals three to four times higher than in the general population in a 30-year Swedish follow-up, even after correcting for comorbid psychopathology. Affirmative commentators have aggressively reinterpreted these data; upon independent reading, the signal remains robust. The fact that this crucial research was ignored by WPATH is not a scientific but a political choice.
Preparation for the pediatric rollout
The 1990s did not yield an empirical breakthrough, but they did provide an infrastructure: specialized clinics, an international network (HBIGDA/WPATH), and the first signs of protocol transfer. The Dutch pediatric rollout from 2000 onwards would build upon this, without the empirical basis being strengthened. Cass (2024) calls this the core problem: the Dutch Protocol from a single center (VUmc, N=70, no control group) was copied internationally for populations for which it had never been tested.
Frequently Asked Questions
Several hundred per year worldwide. Almost exclusively adult men, no minors.
No. Follow-up was retrospective and small-scale; Cass (2024) notes that the evidence base was never seriously built up.
Jon Meyer (1979) concluded that surgical outcomes yielded no psychological advantage over non-operative care. WPATH ignored this.
30-year Swedish follow-up (2011): suicide rates among transitioned individuals three to four times higher than in the general population.
Blanchard's typology (1989): early homosexual transsexuality versus autogynephilia. AGP is a paraphilia, not an identity.
Sources
- Pfafflin, F. (1992). Regrets after Sex Reassignment Surgery. Journal of Psychology & Human Sexuality .
- Blanchard, R. (1989). The Concept of Autogynephilia. Journal of Nervous and Mental Disease .
- Dhejne, C. et al. (2011). Long-term follow-up of transsexual persons. PLOS ONE , 6(2).
- Meyer, J. K. & Reter, D. J. (1979). Sex reassignment. Archives of General Psychiatry .
- Cass, H. (2024). Independent Review—Final Report . NHS England.
- Hruz, P. W. (2020). Deficiencies in scientific evidence. Linacre Quarterly , 87(1).